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Differentially charged isoforms of apolipoprotein E from human blood are potential biomarkers of Alzheimer’s disease

INTRODUCTION: Alzheimer’s disease (AD) is the major cause of dementia among the elderly. Finding blood-based biomarkers for disease diagnosis and prognosis is urgently needed. METHODS: We studied protein distributions in brain tissues, cerebrospinal fluid (CSF), and blood of AD patients by using pro...

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Detalles Bibliográficos
Autores principales: Alzate, Oscar, Osorio, Cristina, DeKroon, Robert M, Corcimaru, Ana, Gunawardena, Harsha P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255367/
https://www.ncbi.nlm.nih.gov/pubmed/25478016
http://dx.doi.org/10.1186/alzrt273