Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer’s disease

INTRODUCTION: Pathologically modified tau protein is the main feature of Alzheimer’s disease (AD) and related tauopathies. Therefore, immunotherapies that target mis-disordered tau represent a promising avenue for the disease-modifying treatment of AD. In this report, we present our discovery of (1)...

Descripción completa

Detalles Bibliográficos
Autores principales: Kontsekova, Eva, Zilka, Norbert, Kovacech, Branislav, Skrabana, Rostislav, Novak, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255369/
https://www.ncbi.nlm.nih.gov/pubmed/25478018
http://dx.doi.org/10.1186/alzrt277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255369/
https://www.ncbi.nlm.nih.gov/pubmed/25478018
http://dx.doi.org/10.1186/alzrt277

Ejemplares similares