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A MATLAB tool for pathway enrichment using a topology-based pathway regulation score

BACKGROUND: Handling the vast amount of gene expression data generated by genome-wide transcriptional profiling techniques is a challenging task, demanding an informed combination of pre-processing, filtering and analysis methods if meaningful biological conclusions are to be drawn. For example, a r...

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Detalles Bibliográficos
Autores principales: Ibrahim, Maysson, Jassim, Sabah, Cawthorne, Michael Anthony, Langlands, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255424/
https://www.ncbi.nlm.nih.gov/pubmed/25367050
http://dx.doi.org/10.1186/s12859-014-0358-2