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An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2

BACKGROUND: Increased activity or expression of integrin-linked kinase (ILK), which regulates cell adhesion, migration, and proliferation, leads to oncogenesis. We identified the molecular basis for the regulation of ILK and its alternative role in conferring ERK1/2/NF-κB-mediated growth advantages...

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Detalles Bibliográficos
Autores principales: Tseng, Po-Chun, Chen, Chia-Ling, Shan, Yan-Shen, Chang, Wen-Teng, Liu, Hsiao-Sheng, Hong, Tse-Ming, Hsieh, Chia-Yuan, Lin, Sheng-Hsiang, Lin, Chiou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255431/
https://www.ncbi.nlm.nih.gov/pubmed/25398317
http://dx.doi.org/10.1186/s12964-014-0069-3