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An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2
BACKGROUND: Increased activity or expression of integrin-linked kinase (ILK), which regulates cell adhesion, migration, and proliferation, leads to oncogenesis. We identified the molecular basis for the regulation of ILK and its alternative role in conferring ERK1/2/NF-κB-mediated growth advantages...
Autores principales: | Tseng, Po-Chun, Chen, Chia-Ling, Shan, Yan-Shen, Chang, Wen-Teng, Liu, Hsiao-Sheng, Hong, Tse-Ming, Hsieh, Chia-Yuan, Lin, Sheng-Hsiang, Lin, Chiou-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255431/ https://www.ncbi.nlm.nih.gov/pubmed/25398317 http://dx.doi.org/10.1186/s12964-014-0069-3 |
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