Overexpression p21WAF1/CIP1 in suppressing retinal pigment epithelial cells and progression of proliferative vitreoretinopathy via inhibition CDK2 and cyclin E

BACKGROUND: P21 is one kind of cyclin-dependent kinase inhibitor that can prevent cells from going through the G1/S phase checkpoint and inhibit cell proliferation. Proliferative vitreoretinopathy (PVR) is a proliferative response in the eye. The aim of this study was to determine whether p21(Waf1/C...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Yuan, Zhigang, You, Caiyun, Han, Jindong, Li, Haiyan, Zhang, Zhuhong, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255444/
https://www.ncbi.nlm.nih.gov/pubmed/25421815
http://dx.doi.org/10.1186/1471-2415-14-144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255444/
https://www.ncbi.nlm.nih.gov/pubmed/25421815
http://dx.doi.org/10.1186/1471-2415-14-144

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