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Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment
INTRODUCTION: Alzheimer’s disease (AD) is characterized by the deposition of tau and amyloid in the brain. Although the core cerebrospinal fluid (CSF) AD biomarkers amyloid β peptide 1–42 (Aβ(1–42)), total tau (t-tau) and phosphorylated tau 181 (p-tau(181)) show good diagnostic sensitivity and speci...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255518/ https://www.ncbi.nlm.nih.gov/pubmed/25478014 http://dx.doi.org/10.1186/alzrt266 |