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Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance

The molecular mechanisms underlying hypothermic neuroprotection have yet to be fully elucidated. Herein we demonstrate that global SUMOylation, a form of post-translational modification with the Small Ubiquitin-like MOdifer, participates in the multimodal molecular induction of hypothermia-induced i...

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Detalles Bibliográficos
Autores principales: Lee, Yang-ja, Mou, Yongshan, Klimanis, Dace, Bernstock, Joshua D., Hallenbeck, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255597/
https://www.ncbi.nlm.nih.gov/pubmed/25538566
http://dx.doi.org/10.3389/fncel.2014.00416