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Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance
The molecular mechanisms underlying hypothermic neuroprotection have yet to be fully elucidated. Herein we demonstrate that global SUMOylation, a form of post-translational modification with the Small Ubiquitin-like MOdifer, participates in the multimodal molecular induction of hypothermia-induced i...
Autores principales: | Lee, Yang-ja, Mou, Yongshan, Klimanis, Dace, Bernstock, Joshua D., Hallenbeck, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255597/ https://www.ncbi.nlm.nih.gov/pubmed/25538566 http://dx.doi.org/10.3389/fncel.2014.00416 |
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