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Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism

The amyloid cascade hypothesis has been the prevailing hypothesis in Alzheimer’s Disease research, although the final and most wanted proof i.e. fully successful anti-amyloid clinical trials in patients, is still lacking. This may require a better in depth understanding of the cascade. Particularly,...

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Detalles Bibliográficos
Autores principales: Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Terwel, Dick, Dewachter, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255655/
https://www.ncbi.nlm.nih.gov/pubmed/25407337
http://dx.doi.org/10.1186/1750-1326-9-51