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NQO2 Is a Reactive Oxygen Species Generating Off-Target for Acetaminophen
[Image: see text] The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity. Here we show that acetaminophen and many structurally related compounds bind quinone reductase...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255684/ https://www.ncbi.nlm.nih.gov/pubmed/25313982 http://dx.doi.org/10.1021/mp5004866 |