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The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story
von Willebrand factor (VWF) plays key roles in both primary and secondary hemostasis by capturing platelets and chaperoning clotting factor VIII, respectively. It is stored within the Weibel–Palade bodies (WPBs) of endothelial cells as a highly prothrombotic protein, and its release is thus necessar...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255685/ https://www.ncbi.nlm.nih.gov/pubmed/23809123 http://dx.doi.org/10.1111/jth.12225 |