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Expression profiling of DNA methylation-mediated epigenetic gene-silencing factors in breast cancer

BACKGROUND: DNA methylation mediates gene silencing primarily by inducing repressive chromatin architecture via a common theme of interaction involving methyl-CpG binding (MBD) proteins, histone modifying enzymes and chromatin remodelling complexes. Hence, targeted inhibition of MBD protein function...

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Detalles Bibliográficos
Autores principales: Kar, Swayamsiddha, Sengupta, Dipta, Deb, Moonmoon, Shilpi, Arunima, Parbin, Sabnam, Rath, Sandip Kumar, Pradhan, Nibedita, Rakshit, Madhumita, Patra, Samir Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255691/
https://www.ncbi.nlm.nih.gov/pubmed/25478034
http://dx.doi.org/10.1186/1868-7083-6-20