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Expression profiling of DNA methylation-mediated epigenetic gene-silencing factors in breast cancer
BACKGROUND: DNA methylation mediates gene silencing primarily by inducing repressive chromatin architecture via a common theme of interaction involving methyl-CpG binding (MBD) proteins, histone modifying enzymes and chromatin remodelling complexes. Hence, targeted inhibition of MBD protein function...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255691/ https://www.ncbi.nlm.nih.gov/pubmed/25478034 http://dx.doi.org/10.1186/1868-7083-6-20 |