Protein–Protein Interfaces from Cytochrome c Oxidase I Evolve Faster than Nonbinding Surfaces, yet Negative Selection Is the Driving Force

Respiratory complexes are encoded by two genomes (mitochondrial DNA [mtDNA] and nuclear DNA [nDNA]). Although the importance of intergenomic coadaptation is acknowledged, the forces and constraints shaping such coevolution are largely unknown. Previous works using cytochrome c oxidase (COX) as a mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Aledo, Juan Carlos, Valverde, Héctor, Ruíz-Camacho, Manuel, Morilla, Ian, López, Francisco Demetrio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255772/
https://www.ncbi.nlm.nih.gov/pubmed/25359921
http://dx.doi.org/10.1093/gbe/evu240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255772/
https://www.ncbi.nlm.nih.gov/pubmed/25359921
http://dx.doi.org/10.1093/gbe/evu240

Ejemplares similares