MCP‐1 downregulates MMP‐9 export via vesicular redistribution to lysosomes in rat portal fibroblasts

Portal fibroblasts (PF) are one of the two primary cell types contributing to the myofibroblast population of the liver and are thus essential to the pathogenesis of liver fibrosis. Monocyte chemoattractant protein‐1 (MCP‐1) is a known profibrogenic chemokine that may be of particular importance in...

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Detalles Bibliográficos
Autores principales: Hickman, DaShawn A., Syal, Gaurav, Fausther, Michel, Lavoie, Elise G., Goree, Jessica R., Storrie, Brian, Dranoff, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255798/
https://www.ncbi.nlm.nih.gov/pubmed/25413315
http://dx.doi.org/10.14814/phy2.12153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255798/
https://www.ncbi.nlm.nih.gov/pubmed/25413315
http://dx.doi.org/10.14814/phy2.12153

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