Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality

Large shifts of osmolality occur in the kidney medulla as part of the urine concentrating mechanism. Hyperosmotic stress profoundly challenges cellular homeostasis and induces endoplasmic reticulum (ER) stress. Here, we examined the unfolded protein response (UPR) in hyperosmotically‐challenged prin...

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Detalles Bibliográficos
Autores principales: Crambert, Gilles, Ernandez, Thomas, Lamouroux, Christine, Roth, Isabelle, Dizin, Eva, Martin, Pierre‐Yves, Féraille, Eric, Hasler, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255800/
https://www.ncbi.nlm.nih.gov/pubmed/25413317
http://dx.doi.org/10.14814/phy2.12169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255800/
https://www.ncbi.nlm.nih.gov/pubmed/25413317
http://dx.doi.org/10.14814/phy2.12169

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