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Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation

Diabetic nephropathy (DN) is a major complication of diabetes and the leading cause of end‐stage renal disease. DN is characterized by changes in kidney structure and function but the underlying genetic and molecular factors are poorly understood. We used a mouse diversity panel to explore the genet...

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Detalles Bibliográficos
Autores principales: Wu, Xiuju, Davis, Richard C., McMillen, Timothy S., Schaeffer, Valerie, Zhou, Zhiqiang, Qi, Hongxiu, Mazandarani, Parisa N., Alialy, Roshanak, Hudkins, Kelly L., Lusis, Aldons J., LeBoeuf, Renée C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255814/
https://www.ncbi.nlm.nih.gov/pubmed/25428948
http://dx.doi.org/10.14814/phy2.12208