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Optimization of ectopic gene expression in skeletal muscle through DNA transfer by electroporation

BACKGROUND: Electroporation (EP) is a widely used non-viral gene transfer method. We have attempted to develop an exact protocol to maximize DNA expression while minimizing tissue damage following EP of skeletal muscle in vivo. Specifically, we investigated the effects of varying injection technique...

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Detalles Bibliográficos
Autores principales: Taylor, Jordan, Babbs, Charlie F, Alzghoul, Mohammed Borhan, Olsen, Aaron, Latour, Mickey, Pond, Amber L, Hannon, Kevin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425588/
https://www.ncbi.nlm.nih.gov/pubmed/15149549
http://dx.doi.org/10.1186/1472-6750-4-11