Malarone treatment failure not associated with previously described mutations in the cytochrome b gene

Malarone(® )(atovaquone-proguanil) is an effective drug for the treatment and prophylaxis of multidrug-resistant falciparum malaria. However, first cases of resistance have been reported, which are associated with mutations at codon 268 of the parasite's cytochrome b gene. We report the first c...

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Detalles Bibliográficos
Autores principales: Wichmann, Ole, Muehlen, Marion, Gruss, Holger, Mockenhaupt, Frank P, Suttorp, Norbert, Jelinek, Tomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425592/
https://www.ncbi.nlm.nih.gov/pubmed/15186499
http://dx.doi.org/10.1186/1475-2875-3-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425592/
https://www.ncbi.nlm.nih.gov/pubmed/15186499
http://dx.doi.org/10.1186/1475-2875-3-14

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