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Malarone treatment failure not associated with previously described mutations in the cytochrome b gene
Malarone(® )(atovaquone-proguanil) is an effective drug for the treatment and prophylaxis of multidrug-resistant falciparum malaria. However, first cases of resistance have been reported, which are associated with mutations at codon 268 of the parasite's cytochrome b gene. We report the first c...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425592/ https://www.ncbi.nlm.nih.gov/pubmed/15186499 http://dx.doi.org/10.1186/1475-2875-3-14 |