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Construction and in vitro evaluation of a recombinant live attenuated PRRSV expressing GM-CSF

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be an important problem for the swine industry. Inactivated vaccines and modified-live virus vaccines are widely used in the field; however, the efficacy of these PRRSV vaccines is suboptimal due to poor immunogenic...

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Detalles Bibliográficos
Autores principales: Yu, Lingxue, Zhou, Yanjun, Jiang, Yifeng, Tong, Wu, Yang, Shen, Gao, Fei, Wang, Kang, Li, Liwei, Xia, Tianqi, Cheng, Qun, Tong, Guangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255968/
https://www.ncbi.nlm.nih.gov/pubmed/25420583
http://dx.doi.org/10.1186/s12985-014-0201-4