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Lattice-Based Model of Ductal Carcinoma In Situ Suggests Rules for Breast Cancer Progression to an Invasive State

Ductal carcinoma in situ (DCIS) is a heterogeneous group of non-invasive lesions of the breast that result from abnormal proliferation of mammary epithelial cells. Pathologists characterize DCIS by four tissue morphologies (micropapillary, cribriform, solid, and comedo), but the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Boghaert, Eline, Radisky, Derek C., Nelson, Celeste M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256017/
https://www.ncbi.nlm.nih.gov/pubmed/25473842
http://dx.doi.org/10.1371/journal.pcbi.1003997