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Arctigenin Increases Hemeoxygenase-1 Gene Expression by Modulating PI3K/AKT Signaling Pathway in Rat Primary Astrocytes

In the present study, we found that the natural compound arctigenin inhibited hydrogen peroxide-induced reactive oxygen species (ROS) production in rat primary astrocytes. Since hemeoxygenase-1 (HO-1) plays a critical role as an antioxidant defense factor in the brain, we examined the effect of arct...

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Detalles Bibliográficos
Autores principales: Jeong, Yeon-Hui, Park, Jin-Sun, Kim, Dong-Hyun, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256028/
https://www.ncbi.nlm.nih.gov/pubmed/25489416
http://dx.doi.org/10.4062/biomolther.2014.121