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Paraquat Induces Apoptosis through Cytochrome C Release and ERK Activation

Paraquat has been suggested to induce apoptosis by generation of reactive oxygen species (ROS). However, little is known about the mechanism of paraquat-induced apoptosis. Here, we demonstrate that extracellular signal-regulated protein kinase (ERK) is required for paraquat-induced apoptosis in NIH3...

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Detalles Bibliográficos
Autores principales: Seo, Hong Joo, Choi, Sang Joon, Lee, Jung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256029/
https://www.ncbi.nlm.nih.gov/pubmed/25489417
http://dx.doi.org/10.4062/biomolther.2014.115