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Arsenite Acutely Decreases Nitric Oxide Production via the ROS—Protein Phosphatase 1—Endothelial Nitric Oxide Synthase-Thr(497) Signaling Cascade

Chronic (>24 h) exposure of arsenite, an environmental toxicant, has shown the decreased nitric oxide (NO) production in endothelial cells (EC) by decreasing endothelial NO synthase (eNOS) expression and/or its phosphorylation at serine 1179 (eNOS-Ser(1179) in bovine sequence), which is associate...

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Detalles Bibliográficos
Autores principales: Seo, Jungwon, Lee, Jee Young, Sung, Min-Sun, Byun, Catherine Jeonghae, Cho, Du-Hyong, Lee, Hyeon-Ju, Park, Jung-Hyun, Cho, Ho-Seong, Cho, Sung-Jin, Jo, Inho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256030/
https://www.ncbi.nlm.nih.gov/pubmed/25489418
http://dx.doi.org/10.4062/biomolther.2014.106