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Arsenite Acutely Decreases Nitric Oxide Production via the ROS—Protein Phosphatase 1—Endothelial Nitric Oxide Synthase-Thr(497) Signaling Cascade
Chronic (>24 h) exposure of arsenite, an environmental toxicant, has shown the decreased nitric oxide (NO) production in endothelial cells (EC) by decreasing endothelial NO synthase (eNOS) expression and/or its phosphorylation at serine 1179 (eNOS-Ser(1179) in bovine sequence), which is associate...
Autores principales: | Seo, Jungwon, Lee, Jee Young, Sung, Min-Sun, Byun, Catherine Jeonghae, Cho, Du-Hyong, Lee, Hyeon-Ju, Park, Jung-Hyun, Cho, Ho-Seong, Cho, Sung-Jin, Jo, Inho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256030/ https://www.ncbi.nlm.nih.gov/pubmed/25489418 http://dx.doi.org/10.4062/biomolther.2014.106 |
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