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ACE2 gene expression is up-regulated in the human failing heart

BACKGROUND: ACE2 is a novel homologue of angiotensin converting enzyme (ACE). ACE2 is highly expressed in human heart and animal data suggest that ACE2 is an essential regulator of cardiac function in vivo. Since overactivity of the renin-angiotensin system contributes to the progression of heart fa...

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Detalles Bibliográficos
Autores principales: Goulter, Andrew B, Goddard, Martin J, Allen, Jennifer C, Clark, Kenneth L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425604/
https://www.ncbi.nlm.nih.gov/pubmed/15151696
http://dx.doi.org/10.1186/1741-7015-2-19