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Structure, Dynamics and Implied Gating Mechanism of a Human Cyclic Nucleotide-Gated Channel

Cyclic nucleotide-gated (CNG) ion channels are nonselective cation channels, essential for visual and olfactory sensory transduction. Although the channels include voltage-sensor domains (VSDs), their conductance is thought to be independent of the membrane potential, and their gating regulated by c...

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Detalles Bibliográficos
Autores principales: Gofman, Yana, Schärfe, Charlotta, Marks, Debora S., Haliloglu, Turkan, Ben-Tal, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256070/
https://www.ncbi.nlm.nih.gov/pubmed/25474149
http://dx.doi.org/10.1371/journal.pcbi.1003976