Ligand design for Rh(iii)-catalyzed C–H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones

We report the regioselective synthesis of dihydroisoquinolones from aliphatic alkenes and O-pivaloyl benzhydroxamic acids mediated by a Rh(iii) precatalyst bearing sterically bulky substituents. While the prototypical Cp* ligand provides product with low selectivity, sterically bulky Cp(t) affords p...

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Detalles Bibliográficos
Autores principales: Hyster, Todd K., Dalton, Derek M., Rovis, Tomislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256080/
https://www.ncbi.nlm.nih.gov/pubmed/25489470
http://dx.doi.org/10.1039/c4sc02590c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256080/
https://www.ncbi.nlm.nih.gov/pubmed/25489470
http://dx.doi.org/10.1039/c4sc02590c

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