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The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

Copper plays an important role in the aetiology and growth of tumours and levels of the metal are increased in the serum and tumour tissue of patients affected by a range of cancers including prostate cancer (PCa). The molecular mechanisms that enable cancer cells to proliferate in the presence of e...

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Detalles Bibliográficos
Autores principales: Gough, Mallory, Blanthorn-Hazell, Sophee, Delury, Craig, Parkin, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256156/
https://www.ncbi.nlm.nih.gov/pubmed/25305487
http://dx.doi.org/10.1016/j.bbrc.2014.10.004