Formation of Linear Amplicons with Inverted Duplications in Leishmania Requires the MRE11 Nuclease

Extrachromosomal DNA amplification is frequent in the protozoan parasite Leishmania selected for drug resistance. The extrachromosomal amplified DNA is either circular or linear, and is formed at the level of direct or inverted homologous repeated sequences that abound in the Leishmania genome. The...

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Detalles Bibliográficos
Autores principales: Laffitte, Marie-Claude N., Genois, Marie-Michelle, Mukherjee, Angana, Légaré, Danielle, Masson, Jean-Yves, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256157/
https://www.ncbi.nlm.nih.gov/pubmed/25474106
http://dx.doi.org/10.1371/journal.pgen.1004805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256157/
https://www.ncbi.nlm.nih.gov/pubmed/25474106
http://dx.doi.org/10.1371/journal.pgen.1004805

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