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Physiologically-Based Toxicokinetic Modeling of Zearalenone and Its Metabolites: Application to the Jersey Girl Study

Zearalenone (ZEA), a fungal mycotoxin, and its metabolite zeranol (ZAL) are known estrogen agonists in mammals, and are found as contaminants in food. Zeranol, which is more potent than ZEA and comparable in potency to estradiol, is also added as a growth additive in beef in the US and Canada. This...

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Detalles Bibliográficos
Autores principales: Mukherjee, Dwaipayan, Royce, Steven G., Alexander, Jocelyn A., Buckley, Brian, Isukapalli, Sastry S., Bandera, Elisa V., Zarbl, Helmut, Georgopoulos, Panos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256163/
https://www.ncbi.nlm.nih.gov/pubmed/25474635
http://dx.doi.org/10.1371/journal.pone.0113632