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Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant
Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of resistance against antifungals. Here we used...
Autores principales: | Wartenberg, Anja, Linde, Jörg, Martin, Ronny, Schreiner, Maria, Horn, Fabian, Jacobsen, Ilse D., Jenull, Sabrina, Wolf, Thomas, Kuchler, Karl, Guthke, Reinhard, Kurzai, Oliver, Forche, Anja, d'Enfert, Christophe, Brunke, Sascha, Hube, Bernhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256171/ https://www.ncbi.nlm.nih.gov/pubmed/25474009 http://dx.doi.org/10.1371/journal.pgen.1004824 |
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