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Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of resistance against antifungals. Here we used...

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Detalles Bibliográficos
Autores principales: Wartenberg, Anja, Linde, Jörg, Martin, Ronny, Schreiner, Maria, Horn, Fabian, Jacobsen, Ilse D., Jenull, Sabrina, Wolf, Thomas, Kuchler, Karl, Guthke, Reinhard, Kurzai, Oliver, Forche, Anja, d'Enfert, Christophe, Brunke, Sascha, Hube, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256171/
https://www.ncbi.nlm.nih.gov/pubmed/25474009
http://dx.doi.org/10.1371/journal.pgen.1004824