Topoisomerase I Plays a Critical Role in Suppressing Genome Instability at a Highly Transcribed G-Quadruplex-Forming Sequence

G-quadruplex or G4 DNA is a non-B secondary DNA structure that comprises a stacked array of guanine-quartets. Cellular processes such as transcription and replication can be hindered by unresolved DNA secondary structures potentially endangering genome maintenance. As G4-forming sequences are highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Puja, Harcy, Victoria, Argueso, Juan Lucas, Dominska, Margaret, Jinks-Robertson, Sue, Kim, Nayun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256205/
https://www.ncbi.nlm.nih.gov/pubmed/25473964
http://dx.doi.org/10.1371/journal.pgen.1004839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256205/
https://www.ncbi.nlm.nih.gov/pubmed/25473964
http://dx.doi.org/10.1371/journal.pgen.1004839

Ejemplares similares