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The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis

IKAROS is a critical regulator of hematopoietic cell fate and its dynamic expression pattern is required for proper hematopoiesis. In collaboration with the Nucleosome Remodeling and Deacetylase (NuRD) complex, it promotes gene repression and activation. It remains to be clarified how IKAROS can sup...

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Detalles Bibliográficos
Autores principales: Bottardi, Stefania, Mavoungou, Lionel, Pak, Helen, Daou, Salima, Bourgoin, Vincent, Lakehal, Yahia A., Affar, El Bachir, Milot, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256266/
https://www.ncbi.nlm.nih.gov/pubmed/25474253
http://dx.doi.org/10.1371/journal.pgen.1004827