Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway

We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome measurements from plaque macrophages from the Reversa mouse w...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramsey, Stephen A., Vengrenyuk, Yuliya, Menon, Prashanthi, Podolsky, Irina, Feig, Jonathan E., Aderem, Alan, Fisher, Edward A., Gold, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256277/
https://www.ncbi.nlm.nih.gov/pubmed/25474352
http://dx.doi.org/10.1371/journal.pgen.1004828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256277/
https://www.ncbi.nlm.nih.gov/pubmed/25474352
http://dx.doi.org/10.1371/journal.pgen.1004828

Ejemplares similares