SHP2 Positively Regulates TGFβ1-induced Epithelial-Mesenchymal Transition Modulated by Its Novel Interacting Protein Hook1

The epithelial-mesenchymal transition (EMT) is an essential process for embryogenesis. It also plays a critical role in the initiation of tumor metastasis. Src homology 2 (SH2)-domain containing protein-tyrosine phosphatase-2 (SHP2) is a ubiquitously expressed protein-tyrosine phosphatase and is mut...

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Detalles Bibliográficos
Autores principales: Li, Shuomin, Wang, Linrun, Zhao, Qingwei, Liu, Yu, He, Lingjuan, Xu, Qinqin, Sun, Xu, Teng, Li, Cheng, Hongqiang, Ke, Yuehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256348/
https://www.ncbi.nlm.nih.gov/pubmed/25331952
http://dx.doi.org/10.1074/jbc.M113.546077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256348/
https://www.ncbi.nlm.nih.gov/pubmed/25331952
http://dx.doi.org/10.1074/jbc.M113.546077

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