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Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity

Human kallikrein-related peptidase 2 (KLK2) is a tryptic serine protease predominantly expressed in prostatic tissue and secreted into prostatic fluid, a major component of seminal fluid. Most likely it activates and complements chymotryptic KLK3 (prostate-specific antigen) in cleaving seminal clott...

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Detalles Bibliográficos
Autores principales:	Skala, Wolfgang, Utzschneider, Daniel T., Magdolen, Viktor, Debela, Mekdes, Craik, Charles S., Brandstetter, Hans, Goettig, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256358/ https://www.ncbi.nlm.nih.gov/pubmed/25326387 http://dx.doi.org/10.1074/jbc.M114.598201

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