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Genetic and Functional Studies of the Intervertebral Disc: A Novel Murine Intervertebral Disc Model

Intervertebral disc (IVD) homeostasis is mediated through a combination of micro-environmental and biomechanical factors, all of which are subject to genetic influences. The aim of this study is to develop and characterize a genetically tractable, ex vivo organ culture model that can be used to furt...

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Detalles Bibliográficos
Autores principales: Pelle, Dominic W., Peacock, Jacqueline D., Schmidt, Courtney L., Kampfschulte, Kevin, Scholten, Donald J., Russo, Scott S., Easton, Kenneth J., Steensma, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256369/
https://www.ncbi.nlm.nih.gov/pubmed/25474689
http://dx.doi.org/10.1371/journal.pone.0112454