Cargando…
Identifying Change Points in a Covariate Effect on Time-to-Event Analysis with Reduced Isotonic Regression
Isotonic regression is a useful tool to investigate the relationship between a quantitative covariate and a time-to-event outcome. The resulting non-parametric model is a monotonic step function of a covariate X and the steps can be viewed as change points in the underlying hazard function. However,...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256386/ https://www.ncbi.nlm.nih.gov/pubmed/25473827 http://dx.doi.org/10.1371/journal.pone.0113948 |