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Dexamethasone Protects Neonatal Hypoxic-Ischemic Brain Injury via L-PGDS-Dependent PGD(2)-DP(1)-pERK Signaling Pathway

BACKGROUND AND PURPOSE: Glucocorticoids pretreatment confers protection against neonatal hypoxic-ischemic (HI) brain injury. However, the molecular mechanism remains poorly elucidated. We tested the hypothesis that glucocorticoids protect against HI brain injury in neonatal rat by stimulation of lip...

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Detalles Bibliográficos
Autores principales: Gonzalez-Rodriguez, Pablo J., Li, Yong, Martinez, Fabian, Zhang, Lubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256424/
https://www.ncbi.nlm.nih.gov/pubmed/25474649
http://dx.doi.org/10.1371/journal.pone.0114470