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Peptide-Based Anti-PCSK9 Vaccines - An Approach for Long-Term LDLc Management

BACKGROUND: Low Density Lipoprotein (LDL) hypercholesterolemia, and its associated cardiovascular diseases, are some of the leading causes of death worldwide. The ability of proprotein convertase subtilisin/kexin 9 (PCSK9) to modulate circulating LDL cholesterol (LDLc) concentrations made it a very...

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Detalles Bibliográficos
Autores principales: Galabova, Gergana, Brunner, Sylvia, Winsauer, Gabriele, Juno, Claudia, Wanko, Bettina, Mairhofer, Andreas, Lührs, Petra, Schneeberger, Achim, von Bonin, Arne, Mattner, Frank, Schmidt, Walter, Staffler, Guenther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256444/
https://www.ncbi.nlm.nih.gov/pubmed/25474576
http://dx.doi.org/10.1371/journal.pone.0114469