Cargando…

Monoacylglycerol Lipase Inhibitor JZL184 Improves Behavior and Neural Properties in Ts65Dn Mice, a Model of Down Syndrome

Genetic alterations or pharmacological treatments affecting endocannabinoid signaling have profound effects on synaptic and neuronal properties and, under certain conditions, may improve higher brain functions. Down syndrome (DS), a developmental disorder caused by triplication of chromosome 21, is...

Descripción completa

Detalles Bibliográficos
Autores principales: Lysenko, Larisa V., Kim, Jeesun, Henry, Cassandra, Tyrtyshnaia, Anna, Kohnz, Rebecca A., Madamba, Francisco, Simon, Gabriel M., Kleschevnikova, Natalia E., Nomura, Daniel K., Ezekowitz, R . Alan B., Kleschevnikov, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256450/
https://www.ncbi.nlm.nih.gov/pubmed/25474204
http://dx.doi.org/10.1371/journal.pone.0114521