Dynamic Scenario of Membrane Binding Process of Kalata B1

Kalata B1 (kB1), a cyclotide that has been used in medical applications, displays cytotoxicity related to membrane binding and oligomerization. Our molecular dynamics simulation results demonstrate that Trp19 in loop 5 of both monomeric and tetrameric kB1 is a key residue for initial anchoring in th...

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Detalles Bibliográficos
Autores principales: Nawae, Wanapinun, Hannongbua, Supa, Ruengjitchatchawalya, Marasri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256454/
https://www.ncbi.nlm.nih.gov/pubmed/25473840
http://dx.doi.org/10.1371/journal.pone.0114473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256454/
https://www.ncbi.nlm.nih.gov/pubmed/25473840
http://dx.doi.org/10.1371/journal.pone.0114473

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