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Protein dynamics and the allosteric transitions of pentameric receptor channels

The recent application of molecular dynamics (MD) methodology to investigate the allosteric transitions of the acetylcholine receptor and its prokaryotic and eukaryotic pentameric homologs has yielded new insights into the mechanisms of signal transduction by these receptors. Combined with available...

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Detalles Bibliográficos
Autor principal: Changeux, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256460/
https://www.ncbi.nlm.nih.gov/pubmed/25505495
http://dx.doi.org/10.1007/s12551-014-0149-z