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Chronic Parasitic Infection Maintains High Frequencies of Short-Lived Ly6C(+)CD4(+) Effector T Cells That Are Required for Protection against Re-infection

In contrast to the ability of long-lived CD8(+) memory T cells to mediate protection against systemic viral infections, the relationship between CD4(+) T cell memory and acquired resistance against infectious pathogens remains poorly defined. This is especially true for T helper 1 (Th1) concomitant...

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Detalles Bibliográficos
Autores principales: Peters, Nathan C., Pagán, Antonio J., Lawyer, Phillip G., Hand, Timothy W., Henrique Roma, Eric, Stamper, Lisa W., Romano, Audrey, Sacks, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256462/
https://www.ncbi.nlm.nih.gov/pubmed/25473946
http://dx.doi.org/10.1371/journal.ppat.1004538