Cargando…

SUMOylation by the E3 Ligase TbSIZ1/PIAS1 Positively Regulates VSG Expression in Trypanosoma brucei

Bloodstream form trypanosomes avoid the host immune response by switching the expression of their surface proteins between Variant Surface Glycoproteins (VSG), only one of which is expressed at any given time. Monoallelic transcription of the telomeric VSG Expression Site (ES) by RNA polymerase I (R...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Farfán, Diana, Bart, Jean-Mathieu, Rojas-Barros, Domingo I., Navarro, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256477/
https://www.ncbi.nlm.nih.gov/pubmed/25474309
http://dx.doi.org/10.1371/journal.ppat.1004545