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SUMOylation by the E3 Ligase TbSIZ1/PIAS1 Positively Regulates VSG Expression in Trypanosoma brucei
Bloodstream form trypanosomes avoid the host immune response by switching the expression of their surface proteins between Variant Surface Glycoproteins (VSG), only one of which is expressed at any given time. Monoallelic transcription of the telomeric VSG Expression Site (ES) by RNA polymerase I (R...
Autores principales: | López-Farfán, Diana, Bart, Jean-Mathieu, Rojas-Barros, Domingo I., Navarro, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256477/ https://www.ncbi.nlm.nih.gov/pubmed/25474309 http://dx.doi.org/10.1371/journal.ppat.1004545 |
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