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CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis

To understand colon cancer metastasis, we earlier analyzed a mouse model that developed liver metastasis of cancer cells disseminated from the spleen. We suggested that CCR1(+) bone marrow (BM)-derived cells are recruited to the microenvironment of disseminated colon cancer cells, and produce metall...

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Detalles Bibliográficos
Autores principales: Hirai, Hideyo, Fujishita, Teruaki, Kurimoto, Kazuki, Miyachi, Hitoshi, Kitano, Satsuki, Inamoto, Susumu, Itatani, Yoshiro, Saitou, Mitinori, Maekawa, Taira, Taketo, M. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256518/
https://www.ncbi.nlm.nih.gov/pubmed/25326065
http://dx.doi.org/10.1007/s10585-014-9684-z